Two changes to Dutch squad as key player is out
De Jong withdrew on Monday after suffering injury on Sunday playing for Barcelona and Real Madrid in their top of the table clash in Spain.
PSV Eindhoven’s Veerman replaces De Jong while Borussia Dortmund striker Malen replaces Steven Bergwijn, who is also out with a knee injury.
The Dutch begin their qualifiers on Friday away against France in Paris, followed by a home game on Monday against Gibraltar in Rotterdam.
Koeman said the absence of De Jong would be a major blow.
"Frenkie has a number of qualities that not many players have. But his absence does not mean that we will suddenly change the system, that would be strange," Koeman told a Monday news conference.