Who's missing: Toney's ban begins and Rashford doubtful for United
Elsewhere, Aston Villa's Philippe Coutinho won't be fit in time to face former club Liverpool, who themselves will be without Darwin Nunez for the match, while Nathan Ake is still missing for Manchester City's final push towards the title.
Take a look at who's out and who may still feature in the upcoming latest round of Premier League fixtures.
Tottenham v Brentford
WILL NOT PLAY
Rodrigo Bentancur (Knee Injury)
Hugo Lloris (Muscle Injury)
Ryan Sessegnon (Thigh Injury)
Pontus Jansson (Thigh Injury)
Keane Lewis-Potter (Knee Injury)
Christian Norgaard (Knock)
Thomas Strakosha (Calf Injury)
Ivan Toney (Suspended)
QUESTIONABLE
Eric Dier (Knock)
Japhet Tanganga (Knock)
Bournemouth v Manchester United
WILL NOT PLAY
Ryan Fredericks (Calf Injury)
Antoine Semenyo (Leg Injury)
Junior Stanislas (Injury)
Marcus Tavernier (Thigh Injury)
Hamed Traore (Ankle Injury)
Mason Greenwood (Inactive)
Tom Heaton (Ankle Injury)
Phil Jones (Knee Injury)
Lisandro Martinez (Leg Injury)
Marcel Sabitzer (Knee Injury)
Donny van de Beek (Knee Injury)
QUESTIONABLE
Marcus Rashford (Illness)
Fulham v Crystal Palace
WILL NOT PLAY
Layvin Kurzawa (Knee Injury)
Andreas Pereira (Ankle Injury)
Tim Ream (Arm Injury)
Nathan Ferguson (Lacking Match Fitness)
Luka Milivojevic (Injury)
James Tomkins (Muscle Injury)
Wilfried Zaha (Thigh Injury)
QUESTIONABLE
Daniel James (Thigh Injury)
Jeffery Schlupp (Knock)
Liverpool v Aston Villa
WILL NOT PLAY
Stefan Bajcetic (Muscle Injury)
Darwin Nunez (Toe Injury)
Calvin Ramsay (Knee Injury)
Thiago (Hip Injury)
Coutinho (Injury)
Jed Steer (Muscle Injury)
QUESTIONABLE
Roberto Firmino (Muscle Injury)
Naby Keita (Muscle Injury)
Wolves v Everton
WILL NOT PLAY
Chiquinho (Knee Injury)
Sasa Kalajdzic (Knee Injury)
Conor Coady (Loan agreement)
Seamus Coleman (Knee Injury)
Ben Godfrey (Groin Injury)
Andros Townsend (Knee Injury)
Ruben Vinagre (Calf Injury)
QUESTIONABLE
Bertrand Traore (Lacking Match Fitness)
Tom Davies (Thigh Injury)
Vitali Mykolenko (Thigh Injury)
Nottingham Forest v Arsenal
WILL NOT PLAY
Guilian Biancone (Knee Injury)
Jack Colback (Head Injury)
Dean Henderson (Thigh Injury)
Scott McKenna (Shoulder Injury)
Omar Richards (Calf Injury)
Jonjo Shelvey (Calf Injury)
Neco Williams (Concussion)
Chris Wood (Thigh Injury)
Mohamed Elneny (Knock)
Gabriel Martinelli (Ankle Injury)
William Saliba (Back Injury)
Takehiro Tomiyasu (Knee Injury)
Oleksandr Zinchenko (Calf Injury)
QUESTIONABLE
Gustavo Scarpa (Knee Injury)
West Ham v Leeds
WILL NOT PLAY
Gianluca Scamacca (Knee Injury)
Tyler Adams (Thigh Injury)
Stuart Dallas (Broken Leg)
Junior Firpo (Red Card)
Luis Sinisterra (Thigh Injury)
QUESTIONABLE
Liam Cooper (Muscle Injury)
Brighton v Southampton
WILL NOT PLAY
Adam Lallana (Thigh Injury)
Tariq Lamptey (Knee Injury)
Solly March (Thigh Injury)
Robert Sanchez (Injury)
Jeremy Sarmiento (Ankle Injury)
Adam Webster (Muscle Injury)
Armel Bella-Kotchap (Injury)
Juan Larios (Muscle Injury)
Tino Livramento (Lacking Match Fitness)
Romain Perraud (Knock)
Mohammed Salisu (Muscle Injury)
QUESTIONABLE
Joel Veltman (Muscle Injury)
Che Adams (Injury)
Manchester City v Chelsea
WILL NOT PLAY
Nathan Ake (Muscle Injury)
Benjamin Mendy (Suspended)
Marcus Bettinelli (Injury)
Armando Broja (Knee Injury)
Ben Chilwell (Muscle Injury)
Marc Cucurella (Thigh Injury)
Reece James (Hamstring Injury)
N'Golo Kante (Groin Injury)
Mason Mount (Pelvis Injury)
QUESTIONABLE
Kalidou Koulibaly (Thigh Injury)
Mateo Kovacic (Knock)
Newcastle v Leicester
TBC
